従来は治療が難しかった病気の治療に期待され、研究が活発に行われている核酸医療の原料を製造販売しています。
AmNA®アミダイド
|
Chemical name / 化学名 |
Abbreviation / 略号 |
CAS No. |
Structure / 構造 |
|---|---|---|---|
| (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxy)-3-(N-benzoyladenine-9-yl)-5-methyl-5-aza-2-oxa-6-oxobicyclo[2.2.1]heptane | AmNA®-A | 1619262-08-6 |  |
| (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxy)- 3-(N-phenoxyacetylguanin-9-yl)-5-methyl-5-aza-2-oxa-6-oxobicyclo[2.2.1]heptane | AmNA®-G | 1619262-26-8 |  |
| (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-(2-cyanoethoxy(diisopropylamino) phosphinoxy)-3-(N-benzoyl-5-methylcytosin-1-yl)-5-methyl-5-aza-2-oxa-6-oxobicyclo[2.2.1]heptane | AmNA®-MeC | 1619262-42-8 |  |
| (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-(2-cyanoethoxy(diisopropylamino) phosphinoxy)-3-(thymin-1-yl)-5-methyl-5-aza-2-oxa-6-oxobicyclo[2.2.1]heptane | AmNA®-T | 1300590-81-1 |  |
■備考
DNA
RNA
核酸医薬
oligonucleotide
ASO /antisense oligonucleotide
BNA /bridged nucleic acid
LNA /linked nucleic acid
sugar-modified nucleic acid
・Amido-bridged nucleic acids (AmNA®s) is protected by Japanese Patent No.5669073 & 6270742,United States Patent No.8541562 and other applications and patents owned by The University of Osaka.
・Products are provided by OSC. to buyers for research use only. The products in their original or any modified form may be used only for the buyer's internal research purposes and not for commercial, diagnostic, non-clinical, clinical, therapeutic, or other use, including use in humans.
・The purchase of products does not include or carry an implied right or license for the buyer to use such products in their original or any modified form for commercial use, including contract research or in the provision of services to third parties. A license must be obtained directly from Luxna Biotech Co., Ltd., granted exclusive license from The University of Osaka. for such uses.
* AmNA is a trademark or registered trademark of Luxna Biotech Co., Ltd.
ペプチド合成試薬（縮合剤、活性エステル用試薬）
|
Chemical name / 化学名 |
Abbreviation / 略号 |
CAS No. |
Structure / 構造 |
|---|---|---|---|
| 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride |
EDC・HCl (WSC, EDAC・HCl) |
25952-53-8 |  |
| N,N'-Dicyclohexylcarbodiimide * | DCC | 538-75-0 |  |
| 1-Hydroxybenzotriazole * | HOBT | 2592-95-2 |  |
| 1-Hydroxybenzotriazole hydrate | HOBT・H2O | 123333-53-9 |  |
| N-Hydroxysuccinimide | NHS | 6066-82-6 |  |
| N-Hydroxy-5-norbornene-2,3-dicarboximide | HONB | 21715-90-2 |  |
| N-Hydroxyphthalimide | HPI | 524-38-9 |  |
* for the Japanese market